Osteoblasts adhere onto a microscopic conglomerate of hydroxyapatite nanoparticles capable of delivering an antibiotic payload to the segments of infected bone.
A silicon nanowire functionalized silica bead (green, center) adhering onto a Caco-2 epithelial monolayer, broadening the intercellular spacing and increasing its drug permeation capacity, while leaving its integrity intact, as evident by the continuous, undisturbed pattern of the perijunctional molecule, ZO-1 (red).
Fluorescently tagged silicon nanowire functionalized silica beads adsorbing on the surface of an in vitro model of intestinal monolayer of epithelial cells.
An osteoblastic cell that has uptaken a cluster of cobalt-doped hydroxyapatite nanoparticles (green) and, resultantly, undergoes a rapture of cytoskeletal filaments (red).
Monodisperse poly-L-lactide-co-glycolide (50:50) nanocapsules for the controlled delivery of Entamoeba histolytica cysteine proteinase inhibitors prepared by controlled precipitation from an alcoholic solution.
Biomimetic continuous titration setting for studying the growth of tooth enamel, the hardest tissue in mammals, and elucidating conditions that would enable noninvasive regeneration of its diseased forms in the clinic.
Plate-shaped cholesterol particles isolated from stable dispersions usable as models for studying the effect of various physicochemical factors on their aggregation, a precondition for the formation of atherosclerotic plaque.
Complex stochiometries of ceramics allow for their use in controlling a wide array of the material properties. Here it is shown how the stoichiometry of nanostructured, superparamagnetic, silica-coated and biocompatible La1-xSrxMnO3+δ (x = 0.16 (□), 0.24 (o), 0.33 (∆) and 0.5 (inverse triangle)) could be used to control the Neel point of the material and tailor it for the most optimal performance as a smart, self-regulating magnetic material applicable in the hyperthermia-based cancer therapies.
Reverse micelles exist in the L2 region of the phase diagram of water and oil based microemulsions and present viable microenvironments for the precipitation of monodisperse nanoparticles with precisely tunable sizes and properties. Shown below is a heart-shaped aggregate of superparamagnetic and uniformly sized, spherical, 6-nm sized particles of Ni0.5Zn0.5Fe2O4 obtained in reverse micelles composed of CTAB and water dispersed in 1-hexanol.